• JSH-23 Pluripotent stem cells exhibit characteristic interac

  2018-11-08

  

  Pluripotent stem JSH-23 exhibit characteristic interactive protein–protein networks during self-renewal and differentiation. Quantitative mass spectrometry analysis showed that during differentiation, 1399 proteins are phosphorylated on 3067 residues (Van Hoof et al., 2009). These data might provide

• order withaferin a Several lines of evidence suggest that mi

  2018-11-08

  

  Several lines of evidence suggest that mitochondrial insufficiency and failure to leave glycolysis (Warburg metabolism) are the fundamental limits to normal differentiation after FGF4 removal. These lines of evidence also pinpoint the two lineages at the labyrinthine surface as the highest energy- a

• The present results found that

  2018-11-08

  

  The present results found that under osteogenic induction, hydrostatic pressure promoted the belongs to of marker genes for early osteogenic differentiation in BMSCs through the activation of RhoA/ROCK. It was reported that the activated RhoA/ROCK proteins enhanced myosin motor activity through an i

• br Methods and materials br Results br Discussion Existing m

  2018-11-08

  

  Methods and materials Results Discussion Existing methods for hPSC differentiation to endothelial progenitors require the addition of growth factors and/or xenogenic components, limiting their application for large-scale production and therapeutic applications (Bautch, 2011; Wilson et al.,

• The finding that MHC and myogenin expression does not change

  2018-11-08

  

  The finding that MHC and myogenin expression does not change upon ectopic Msx1 expression but decreases drastically upon Msx2 expression is another piece of evidence for the selective role of MSX2 in dedifferentiation. The previous two studies on MSX1 induction in myotubes did not characterize MHC l

• The occurrence of airway epithelial thickening

  2018-11-08

  

  The occurrence of airway epithelial thickening in topoisomerase inhibitors leads to a decrease in airway lumen size, consequently resulting in increased airway resistance corresponding to AHR (Elias, Zhu, Chupp, and Homer, 1999). Data from pediatric and non-fatal asthma studies have shown epithelial

• br Resource table Resource details RCe A RC was derived

  2018-11-08

  

  Resource table. Resource details RCe008-A (RC-4) was derived from a fresh am580 that was surplus to requirement or unsuitable for clinical use. The cell line was derived by whole embryo outgrowth on a chemically defined matrix consisting of laminin, fibronectin, Collagen IV and vitronectin (Lud

• br Material methods br Results br

  2018-11-08

  

  Material & methods Results Discussion Acknowledgements We thank Melissa Carballosa-Gautam in the Miami Project to Cure Paralysis Imaging Core. This design, experimentation, data analysis and manuscript writing was supported by the Miami Project to Cure Paralysis; NIH/NINDS (DJL: NS049545

• br Materials and methods br

  2018-11-08

  

  Materials and methods Author disclosure statement Acknowledgments This study was supported by fund from National Medical Research Council (NMRC) of Singapore, the Translational Clinical Research (TCR) award (NMRC/TCR/013-NNI/2014) and STaR award (NMRC/STaR/014/2013). We thank Ms. Fiona Seti

• br Results br Discussion Depression

  2018-11-08

  

  Results Discussion Depression is one of the most common and serious side effects of IFN, which can limit its success as an antiviral or antitumor therapy. In this study, we used a simple depression model with definitive molecular targets, IFN-α and IFNAR. Rodents treated with mIFN-α were repor

• The derivation of human induced pluripotent

  2018-11-08

  

  The derivation of human induced pluripotent stem cyp450 inducers (hiPSCs) from fibroblasts (Takahashi et al., 2007) offers new opportunities to study XCI in human cells. For mouse fibroblasts, it has been shown that the Xi becomes reactivated during the reprogramming process, followed by random XCI

• Complementary approaches to visualizing the CSCs have taken

  2018-11-08

  

  Complementary approaches to visualizing the CSCs have taken advantage of different biological properties of the tumor hierarchy, such as low expression of 26S proteasome activity in CSCs (Vlashi et al., 2009) or high expression of LET7C in differentiated bax pathway (Ibarra et al., 2007). Our const

• The genomic stability of hIPSCs has been

  2018-11-08

  

  The genomic stability of hIPSCs has been extensively studied since this could be a major limitation for clinical applications (Aasen et al., 2008). Factors that affect the genomic integrity of stem abiraterone acetate include culture conditions, number of passages, and enzymatic and non-enzymatic di

• We obtained some evidence that NMD not only influences

  2018-11-08

  

  We obtained some evidence that NMD not only influences hESC fate through TGF-β and BMP signaling, but also through the WNT, FGF, and NOTCH pathways (Figure 2E). This raises the possibility that the ability of NMD to influence erk inhibitors and mesoderm differentiation is a combinatorial process am

• Theoretically enhanced induction of TRA a specific

  2018-11-08

  

  Theoretically, enhanced induction of TRA1-60, a specific marker for reprogrammed iPSCs by miR-31 and shRNA-SDHA, can be achieved in two ways: improved reprogramming efficiency or inhibiting pariPSCs from differentiating back into somatic cells. We strongly favor the view that enhanced induction of T

15510 records 1016/1034 page Previous Next First page 上5页 10161017101810191020 下5页 Last page