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order l-ascorbic acid Given the phase trial results we sough
2018-11-05
Given the phase 1 trial results, we sought to address a complementary question whether VIS410 could be successfully deployed in the event of an epidemic outbreak to improve public health outcomes. We predicted that given VIS410\'s half-life, its distribution to the primary site of influenza A infect
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An important implication of our results
2018-11-05
An important implication of our results is that they point to the correct ‘scale’ of analysis that addresses the possibility of H 89 in FSE-L and malfunction in FSE-NL. The results best represent the ‘meso-scale’ level of analysis between physiological alterations due to FSE and observable differenc
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br Materials and Methods br Results
2018-11-05
Materials and Methods Results Discussion The thoracic aortic aneurysm in BAV patients frequently involves ascending aorta, where the SMCs are derived from the neural crest. In contrast, patients with BAV rarely have aneurysms involving the descending thoracic aorta, and the SMCs in this reg
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Sample collection for a cohort is often
2018-11-05
Sample collection for a cohort is often carried out at the time of diagnosis, time of treatment or time of screening of healthy individuals, and not confined to a certain time of the year. This implies that environmental factors, such as pollen concentration in the spring, may cause downstream effec
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Consistent with the phenotypic response to ANXA
2018-11-05
Consistent with the phenotypic response to ANXA suppression (Fig. 6), suppression of ANXA2 led to an alteration of not only mesenchymal signatures but also cell cycle related pathways, such as cell cycle checkpoint genes (Gene Set Enrichment Analysis p=8.6×10, q=8.6×10, Supp Table 1). Intriguingly,
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Secondly we have demonstrated that
2018-11-05
Secondly, we have demonstrated that BCAA increased adipocyte lipolysis and FFA release via AMPKα2-dependent HSL activation. Lipolysis rates are precisely regulated through hormonal and biochemical signals. Initiation of TG hydrolysis in adipose tissue is controlled by two enzymes, HSL and ATGL (also
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Concussion is the most common type of
2018-11-05
Concussion is the most common type of traumatic transcription factors injury (). Research into concussion has significantly increased in the past decade reflecting the growing recognition of repeated head-injuries in sport. Whilst the focus of the research has centred on those who have been concuss
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Helminth immunotherapy is also being
2018-11-05
Helminth immunotherapy is also being evaluated as a therapy for MS, with varying success. So far, clinical trials with TSO in the context of MS have demonstrated modest to no clinical improvement (Wolff et al., 2012). However, in a prospective study where MS patients were enrolled during remission,
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br Tectonomagmatic setting and metallogeny The Hecaokeng
2018-11-05
Tectonomagmatic setting and metallogeny The Hecaokeng uranium ore field is situated approximately 100 km east-southeast of Ganzhou City, southern Jiangxi Province, Southeast China (Fig. 1). It lies in the central part of the Cathaysia Block of Proterozoic age, which is separated from the older Ya
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Conversely the implementation of CBT i e the systematic
2018-11-05
Conversely, the implementation of CBT (i.e., the systematic application of the principles and learning techniques needed to evaluate and improve behavior) has not been well studied with regard to narcolepsy, most likely because As Fig. 1 shows, however, 32.4% of psychologists who are trained in CBT
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Adan and Natale in a study conducted in Barcelona involving
2018-11-05
Adan and Natale (2002), in a study conducted in Barcelona involving 2135 individuals with age between 17 and 30 years, verified association between the male gender and eveningness [40]. In the same year, in Brazil, Hidalgo et al. (2003) investigated 318 individuals of the same age, obtaining the sam
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Conclusively both questionnaires were found to be psychometr
2018-11-05
Conclusively, both questionnaires were found to be psychometrically valid instruments that allow a screening about adolescents׳ and parents׳ perceptions about sleep, according to three dimensions and respective nine sub-dimensions, materialized in a model of education which includes sleep behavioral
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lipid metabolism pathway Some countries with socialized medi
2018-11-05
Some countries with socialized medicine concerned with optimizing resources and implementing practical methods to diagnose prevalent diseases have conducted telemedicine experiences for the diagnosis of OSA. Recently, Coma del Corral et al. have published the results of the pilot study they carried
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br Materials and methods br Results br Discussion Discovery
2018-11-05
Materials and methods Results Discussion Discovery and characterization of cancer-associated markers effective in cancer diagnosis and treatment is a main focus in modern medicine. Several targets have been described [13,14]. Furthermore, we recently showed that the malarial VAR2CSA protein
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The authors have previously hypothesized
2018-11-05
The authors have previously hypothesized that CHC that changes to the vestibular mucosa induced by CHCs are a potential cause of vestibulodynia [11]. Herein, we describe our treatment approach to and clinical outcomes in premenopausal women with vestibulodynia who presented to a vulvar pain clinic w
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