• These characteristics of Tat secretion are remarkably overla

  2018-10-23

  

  These characteristics of Tat secretion are remarkably overlapping with those of cellular FGF-2, which is also sensitive to ouabain and involves binding of the factor to the Na+,K+-ATPase (Dahl et al., 2000; Florkiewicz et al., 1998; Smith et al., 2001; Trudel et al., 2000; Zeitler et al., 2015), whi

• br Senolytics Pre clinical Studies Demonstrating Phenotype A

  2018-10-23

  

  Senolytics: Pre-clinical Studies Demonstrating Phenotype Alleviation In mice, senolytics alleviate a range of conditions that have been associated with effects of senescent cells. So far, these include effects on cardiac, vascular, metabolic, neurological, radiation-induced, chemotherapy-induced,

• The clinical definition of frailty remains controversial

  2018-10-23

  

  The clinical definition of frailty remains controversial, but one validated measure is the Frailty Index, where frailty is the result of an accumulation of health deficits over time, and the severity of frailty can predict adverse health outcomes (Rockwood and Mitnitski, 2007). In the general popul

• We also found that CCDC can associate with stabilize and

  2018-10-23

  

  We also found that CCDC170 can associate with, stabilize, and bundle, perinuclear MTs (Figs. 2 and 4), possibly creating a perinuclear “track” for Golgi organization (Fig. 3 and Fig. S7). We also showed both by imaging and Western blotting that overexpression of CCDC170 leads to increases in the lev

• For HCC the second leading cause of cancer death

  2018-10-23

  

  For HCC, the second leading cause of cancer death worldwide, there is a lack of effective drugs. The only approved drug, sorafenib, has modest survival benefits (Llovet et al., 2008; Abou-Alfa et al., 2006; Cheng et al., 2009). Immunotherapy has been considered as an effective approach for cancer tr

• br Data sets and attributes The data published here are

  2018-10-23

  

  Data sets and attributes The data published here are organized in two ‘csv’ files, ‘rawdata.csv.gz’ (4.5MB) and ‘features.csv’ (200kB). The raw data are stored in the first file ‘rawdata.csv.gz’, where each line represents a single measurement per sensor. Consequently, one needs to read specific

• br Data experimental design materials and

  2018-10-23

  

  Data, experimental design, materials and methods Materials and methods Data Acknowledgements The authors thank the Ministry of Science and Technology (103-2314-B-002 -023 -MY3), the National Taiwan University Hospital, and the Taipei City Hospital, Taiwan, for their financial support. Th

• br Acknowledgements br Data Silver resistance genes

  2018-10-23

  

  Acknowledgements Data Silver resistance genes are part of a plasmid-associated gene cluster that encodes a silver binding protein (silE), efflux pump (silA and silP), and a membrane sensor kinase (silS) [2]. Melting curve analysis was performed to determine the specificity of the PCR products

• br Conclusions br Acknowledgements The authors wish

  2018-10-22

  

  Conclusions Acknowledgements The authors wish to express their sincere thanks to M/s Mailam India Ltd, Pondicherry, India for providing the funds to carry out this autophagy inhibitor research work through Mailam India Research (MIR) Fellowship, M/s Salzgitter Mannesmann Stainless Tubes Itali

• Experimental trials were created using

  2018-10-22

  

  Experimental trials were created using full factorial experiments by Design of Experiments (DoE) as per Table 2. Low alloy steel (T11) tube with 48 mm outer diameter and 6 mm thickness was chosen for study. Different dimensions of piping could be accommodated by changing the MIAB weld head. The chem

• Dado que solo entrevistamos a Pat y no a alguna

  2018-10-22

  

  Dado que solo entrevistamos metabotropic glutamate receptor Pat y no a alguna de sus trabajadoras, es imposible saber si alguna de las migrantes que ella emplea de forma indirecta están trabajando para pagar la deuda en la que incurrieron durante el proceso migratorio, pero otras investigaciones rea

• Introduction The Stone Age and Bronze Age were named for

  2018-10-22

  

  Introduction The Stone Age and Bronze Age were named for the materials that dominated these major historical periods. Consequently, the modern era, which is encountering an ever-increasing necessary of ceramic materials for industrial or biomedical use, could be characterized as the “Ceramic Age”.

• Although Indian banks have largely

  2018-10-22

  

  Although Indian banks have largely been able to adhere to guidelines of Reserve Bank of India for managing liquidity, factors affecting liquidity in Indian banks remain relatively unidentified owing to a scarcity of studies on management of liquidity in Indian banks (Bhati & De Zoysa, 2012). The re

• br Materials and methods br Results br Discussion The patien

  2018-10-22

  

  Materials and methods Results Discussion The patients in burn wards are more susceptible to infection than those in other common wards, and wound infection in burn patients is a difficult problem. The previous study illustrated that the patients in younger ages and owned larger burn sizes a

• Also central to architectural education and

  2018-10-22

  

  Also central to architectural education and practice are management, verbal and written communication skills. These will enable them to effectively perform their leadership role in the building industry. Jules (1979) further contends that even though mathematics can be counted upon for generation of

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