• Consistent with the phenotypic response to ANXA

  2018-11-05

  

  Consistent with the phenotypic response to ANXA suppression (Fig. 6), suppression of ANXA2 led to an alteration of not only mesenchymal signatures but also cell cycle related pathways, such as cell cycle checkpoint genes (Gene Set Enrichment Analysis p=8.6×10, q=8.6×10, Supp Table 1). Intriguingly,

• Secondly we have demonstrated that

  2018-11-05

  

  Secondly, we have demonstrated that BCAA increased adipocyte lipolysis and FFA release via AMPKα2-dependent HSL activation. Lipolysis rates are precisely regulated through hormonal and biochemical signals. Initiation of TG hydrolysis in adipose tissue is controlled by two enzymes, HSL and ATGL (also

• Concussion is the most common type of

  2018-11-05

  

  Concussion is the most common type of traumatic transcription factors injury (). Research into concussion has significantly increased in the past decade reflecting the growing recognition of repeated head-injuries in sport. Whilst the focus of the research has centred on those who have been concuss

• Helminth immunotherapy is also being

  2018-11-05

  

  Helminth immunotherapy is also being evaluated as a therapy for MS, with varying success. So far, clinical trials with TSO in the context of MS have demonstrated modest to no clinical improvement (Wolff et al., 2012). However, in a prospective study where MS patients were enrolled during remission,

• br Tectonomagmatic setting and metallogeny The Hecaokeng

  2018-11-05

  

  Tectonomagmatic setting and metallogeny The Hecaokeng uranium ore field is situated approximately 100 km east-southeast of Ganzhou City, southern Jiangxi Province, Southeast China (Fig. 1). It lies in the central part of the Cathaysia Block of Proterozoic age, which is separated from the older Ya

• Conversely the implementation of CBT i e the systematic

  2018-11-05

  

  Conversely, the implementation of CBT (i.e., the systematic application of the principles and learning techniques needed to evaluate and improve behavior) has not been well studied with regard to narcolepsy, most likely because As Fig. 1 shows, however, 32.4% of psychologists who are trained in CBT

• Adan and Natale in a study conducted in Barcelona involving

  2018-11-05

  

  Adan and Natale (2002), in a study conducted in Barcelona involving 2135 individuals with age between 17 and 30 years, verified association between the male gender and eveningness [40]. In the same year, in Brazil, Hidalgo et al. (2003) investigated 318 individuals of the same age, obtaining the sam

• Conclusively both questionnaires were found to be psychometr

  2018-11-05

  

  Conclusively, both questionnaires were found to be psychometrically valid instruments that allow a screening about adolescents׳ and parents׳ perceptions about sleep, according to three dimensions and respective nine sub-dimensions, materialized in a model of education which includes sleep behavioral

• lipid metabolism pathway Some countries with socialized medi

  2018-11-05

  

  Some countries with socialized medicine concerned with optimizing resources and implementing practical methods to diagnose prevalent diseases have conducted telemedicine experiences for the diagnosis of OSA. Recently, Coma del Corral et al. have published the results of the pilot study they carried

• br Materials and methods br Results br Discussion Discovery

  2018-11-05

  

  Materials and methods Results Discussion Discovery and characterization of cancer-associated markers effective in cancer diagnosis and treatment is a main focus in modern medicine. Several targets have been described [13,14]. Furthermore, we recently showed that the malarial VAR2CSA protein

• The authors have previously hypothesized

  2018-11-05

  

  The authors have previously hypothesized that CHC that changes to the vestibular mucosa induced by CHCs are a potential cause of vestibulodynia [11]. Herein, we describe our treatment approach to and clinical outcomes in premenopausal women with vestibulodynia who presented to a vulvar pain clinic w

• br Conclusion and Recommendations for Research The emerging

  2018-11-03

  

  Conclusion and Recommendations for Research The emerging field of Nutritional Psychiatry offers promise for a new approach to both the prevention and treatment of disorders that account for the leading disability burden globally. Such investigations are also of relevance to neurodevelopmental (Bo

• Claudin is a structural protein of the tight junction

  2018-11-03

  

  Claudin-4 is a structural protein of the tight junction that augments epithelial barrier function in vitro (Turner, 2009; Gunzel and Yu, 2013) and has been characterized in vivo as a paracellular anion channel (Hou et al., 2010). Maintenance of tight junctions requires the physical apposition of ad

• A diferencia del consenso casi generalizado

  2018-11-03

  

  A diferencia del consenso casi generalizado que existe en los estudios vegf tyrosine kinase inhibitor nivel de empresa, con datos a nivel de industria no existe un acuerdo del impacto de las tic en el crecimiento, e incluso, cuando llega a haber coincidencia, la magnitud del impacto difiere de maner

• SCR 7 The results of the direct quasistatic calculations of

  2018-11-03

  

  The results of the direct, quasistatic calculations of the bulk value of the Young׳s modulus in step (2) are summarized in Table 2. k-points for the tetragonal and orthorhombic unit SCR 7 were also chosen according to the Monkhorst–Pack scheme. In Table 2 the number of divisions n, however, refers

15188 records 998/1013 page Previous Next First page 上5页 9969979989991000 下5页 Last page