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br Role of the funding source br Introduction Myeloprolifera
2019-06-24

Role of the funding source Introduction Myeloproliferative neoplasms (MPNs) are stem-cell-derived disorders that cause overproduction of one or more of the formed elements of the blood. MPNs include chronic myelogenous leukemia (CML) and the Philadelphia-negative MPNs: polycythemia vera (PV),
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br Discussion A familial platelet disorder
2019-06-24

Discussion A familial platelet disorder with a propensity to myeloid malignancy (FPD/MM) was first reported in 1978 and since then approximately 30 pedigrees with RUNX1 germline mutations have been reported in the literature [9,11]. The RUNX1 gene is composed of 10 exons (1–6, 7A, 7B, 7C and 8).
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br A few years ago my
2019-06-24

A few years ago, my group published an article entitled uhuru. is the Swahili word for “freedom”. The idea was to highlight the plight of patients with end-stage kidney disease (ESKD) and the challenges and frustrations of their nephrologists in sub-Saharan Africa amidst health-care authorities th
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It is recommended that pilsicainide be administered over min
2019-06-24

It is recommended that pilsicainide be administered over 10min, with 1.0mg/kg being the maximum daily dosage allowed. However, a single oral dose of pilsicainide has been shown to be effective, feasible and safe, and the single dose is always from 100 to 150mg [4,10]. Both the time to maximum drug c
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NVP DPP 728 dihydrochloride Arita et al reported that the me
2019-06-24

Arita et al. reported that the mechanism of ST-segment elevation in inferior leads is right coronary artery hypoperfusion due to vasodilation by Bezold–Jarisch-like reflexes that are induced by stimulation of the NVP DPP 728 dihydrochloride in the intra-atrial septum during transseptal puncture and
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br Cardiac imaging br Head
2019-06-24

Cardiac imaging Head-up tilt testing Head-up tilt (HUT) testing is recommended to judge an episode of syncope to be likely caused by VF by excluding neurally mediated syncope (NMS). However, NMS may coexist with Brugada syndrome [42]. We conducted HUT testing in 46 patients with type-1 Brugada
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br Case report The patient was an month
2019-06-24

Case report The patient was an 11-month-old boy. No abnormalities were observed throughout the embryonic stage and perinatal period. When he was 11 months and 10 day old, he suddenly developed pallor and poor responsiveness, with his eyes rolled back in his head, which continued for approximately
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A recent analysis recommended axillary staging by sentinel l
2019-06-24

A recent analysis recommended axillary staging by sentinel lymph node biopsy, and administration of adjuvant radiotherapy and endocrine therapy after breast conserving surgery for mucinous carcinoma. Park et al. concluded that adjuvant chemotherapy could potentially be omitted in cases with favorab
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The majority of breast malignancies are hormone responsive a
2019-06-24

The majority of breast malignancies are hormone responsive, and adjuvant endocrine therapy is used routinely to prevent breast cancer recurrence and death [6,7]. Tamoxifen was the past treatment of choice for endocrine-responsive postmenopausal breast cancer and was found to preserve BMD in postmeno
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Tetrazole what br Mechanisms of arrhythmias Several schemes
2019-06-24

Mechanisms of arrhythmias Several schemes have been used to classify the mechanisms of cardiac arrhythmias. Traditionally, these have been divided into nonreentrant and reentrant activity [11]. An alternative scheme divided them into those occurring at the cellular and tissue levels [12]. A dynam
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A decreasing trend in CRT D implantation
2019-06-24

A decreasing trend in CRT-D implantation has been reported recently, based on the database from the National Inpatient Sample in the USA [20]. They found that advancing age and an increasing comorbidity burden were associated with a reduced likelihood of CRT-D, and speculated that the decline in CRT
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Cy3 NHS ester (non-sulfonated) The aim of this cross section
2019-06-24

The aim of this cross-sectional study was to investigate the relationships between patient characteristics and antithrombotic therapy prescribed for the prevention of ischemic stroke and systemic embolism in patients with NVAF in clinical practice. Additionally, because the data were to be used to c
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br On Nov every year the International Day for
2019-06-24

On Nov 25 every year, the International Day for the Elimination of Violence Against Women, and the 16 days of activism that follow it, help to draw the world\'s attention to the scourge of intimate partner violence and other forms of gender-based violence and their harmful effects on women\'s heal
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br In their Comment on the use of
2019-06-24

In their Comment on the use of antenatal corticosteroids to reduce preterm infant deaths, Kishwar Azad and Anthony Costello advise “extreme caution” before scale-up in low-income settings. They emphasise maternal sepsis as a concern but cite only one trial in which dexamethasone resulted in a sign
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All patients with rickettsial infections
2019-06-24

All patients with rickettsial infections reported by Dittrich and colleagues presented with fever at admission, and few patients presented with typical eschars of inoculation (only 3·6% of patients with murine typhus and 6·7% with scrub typhus). This finding might be a result of poor awareness about
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