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Antzelevitch and colleagues have long suggested
2019-04-29
Antzelevitch and colleagues have long suggested an alternative explanation [31,73,74]. Loss of the somatostatin agonist (AP), which has been shown in experimental models to create the arrhythmogenic substrate in BrS, leads to contractile changes that could explain the wall motion abnormalities obse
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br Conclusion Extensive studies over the
2019-04-29
Conclusion Extensive studies over the past two decades have significantly expanded our knowledge of the physiological and pathophysiological functions of bile nf-κb inhibitor metabolism and signaling. Bile acids are no longer considered merely physiological detergent molecules that facilitate nut
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ionophores Second despite the paper s emphasis on social
2019-04-29
Second, despite the paper\'s emphasis on social justice, its policy recommendations (zinc supplementation, fortification of staple foods, application of zinc-containing fertilisers to food crops, biofortification of staple crops, and cross-breeding of staples with varieties with less nutritional sen
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Most forms of AVNRT are created by
2019-04-28
Most forms of AVNRT are created by reentry between two (or more) atrial connections to the AV node. The fast AV nodal pathway (shortest conduction time) is formed by transitional cells crossing the tendon of Todaro superiorly. Two slow AV nodal pathways are formed by the rightward and leftward infer
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br Conclusion and future research Many new findings from phy
2019-04-28
Conclusion and future research Many new findings from physical-chemical, biochemical, genetic, and molecular biological studies of gallstones in humans and animals have clearly demonstrated that interactions of five primary defects lead to the formation of cholesterol gallstones. A novel concept
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Karyotypic analysis is commonly used in
2019-04-28
Karyotypic analysis is commonly used in the diagnostic work up of various hematological diseases. Some chromosome abnormalities are specifically associated with certain diseases or disease subtypes [4,5]. The detection of various chromosomal alterations not only assists in diagnosis, but also helps
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Given the absence of data
2019-04-28
Given the absence of data from level I hospitals and a lack of clarity on the distribution of births among different levels of hospitals excluded from the sampling, the capacity of Zhu and colleagues\' study to represent the national population is limited, and the stillbirth rate could be biased. Fu
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br Acknowledgments This study was
2019-04-28
Acknowledgments This study was supported by a grant from the National Science Council (NSC 98-2314-B-075B-007-MY2). Introduction Many complications may occur following treatment of femoral shaft open fracture such as nonunion, malunion, delay union, bone defect, bone and joint deformity or st
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Purkinje potentials have been identified
2019-04-28
Purkinje potentials have been identified in some cases of successful ablation of PVCs originating in the right ventricular papillary muscles, indicating a possible involvement of the Purkinje fibers as well as the left ventricular papillary muscles [3,4]. During our first procedure, a Purkinje poten
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The main products of EBM are evidence based guidelines
2019-04-28
The main products of EBM are evidence-based guidelines (EBGs), “systematically developed statements to assist practitioner and patient decision about appropriate health care for specific clinical circumstances” [21]. EBGs indeed substantially improve clinical care [29]. Preliminary steps for guidel
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Having to seek various approvals with
2019-04-28
Having to seek various approvals, with no communication between RECs and no plan for which committee\'s decisions take priority, can lead to research bottlenecks. Many RECs, particularly those in low-income and middle-income countries (LMICs), have long turnaround times, perhaps because of infrequen
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br It s that time of
2019-04-28
It\'s that time of year again when we ask readers to submit photographs for our annual Highlights photography competition. We are looking for striking images that arrest our attention about any topic in medicine, from global health to clinical medicine, from the individual person to populations. A
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Las colaboraciones de Woinoff conforman el
2019-04-28
Las colaboraciones de “Woinoff ” conforman el último vértice de la constelación intelectual que, hematopoietic stem cells nuestro juicio, pudo haber ayudado en el cambio intelectual de Bilbao. En ellas, el pretendido “atraso” se vuelve reserva moral desde la cual la democracia radical europea puede
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In addition further study is required
2019-04-28
In addition, further study is required to evaluate whether identified mutations influence post-translational modifications because they are important mechanism of transcription factors for regulating normal and leukemic hematopoiesis. Authors\' contributions Conflict of interest Acknowledgm
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Although second malignancies are increasingly observed
2019-04-28
Although second malignancies are increasingly observed after NHL, the incidence of CLL and RCC in the same patient is exceptional [4,5]. Nishikubo et al. [4] reported a case series of 8 patients with lymphoid malignancies and RCC. In 2 of 8 patients, CLL and T-cell CLL were diagnosed 1 year and 8 mo
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