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br Acknowledgments This study was
2019-04-28

Acknowledgments This study was supported by a grant from the National Science Council (NSC 98-2314-B-075B-007-MY2). Introduction Many complications may occur following treatment of femoral shaft open fracture such as nonunion, malunion, delay union, bone defect, bone and joint deformity or st
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Purkinje potentials have been identified
2019-04-28

Purkinje potentials have been identified in some cases of successful ablation of PVCs originating in the right ventricular papillary muscles, indicating a possible involvement of the Purkinje fibers as well as the left ventricular papillary muscles [3,4]. During our first procedure, a Purkinje poten
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The main products of EBM are evidence based guidelines
2019-04-28

The main products of EBM are evidence-based guidelines (EBGs), “systematically developed statements to assist practitioner and patient decision about appropriate health care for specific clinical circumstances” [21]. EBGs indeed substantially improve clinical care [29]. Preliminary steps for guidel
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Having to seek various approvals with
2019-04-28

Having to seek various approvals, with no communication between RECs and no plan for which committee\'s decisions take priority, can lead to research bottlenecks. Many RECs, particularly those in low-income and middle-income countries (LMICs), have long turnaround times, perhaps because of infrequen
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br It s that time of
2019-04-28

It\'s that time of year again when we ask readers to submit photographs for our annual Highlights photography competition. We are looking for striking images that arrest our attention about any topic in medicine, from global health to clinical medicine, from the individual person to populations. A
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Las colaboraciones de Woinoff conforman el
2019-04-28

Las colaboraciones de “Woinoff ” conforman el último vértice de la constelación intelectual que, hematopoietic stem cells nuestro juicio, pudo haber ayudado en el cambio intelectual de Bilbao. En ellas, el pretendido “atraso” se vuelve reserva moral desde la cual la democracia radical europea puede
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In addition further study is required
2019-04-28

In addition, further study is required to evaluate whether identified mutations influence post-translational modifications because they are important mechanism of transcription factors for regulating normal and leukemic hematopoiesis. Authors\' contributions Conflict of interest Acknowledgm
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Although second malignancies are increasingly observed
2019-04-28

Although second malignancies are increasingly observed after NHL, the incidence of CLL and RCC in the same patient is exceptional [4,5]. Nishikubo et al. [4] reported a case series of 8 patients with lymphoid malignancies and RCC. In 2 of 8 patients, CLL and T-cell CLL were diagnosed 1 year and 8 mo
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br We have reviewed the issues and arguments
2019-04-26

We have reviewed the issues and arguments presented by Wang et al. In fact, we have well-clarified these issues in “Discussion” section of our original article. The aim of our study was to investigate the expression of maternal antineuronal ritodrine hydrochloride and their role in childhood aut
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Polymorphic VT VF storms can occur
2019-04-26

Polymorphic VT/VF storms can occur in patients with severe buy Oxamflatin failure, independent of their underlying causes. Recent experimental studies using a pacing-induced heart failure model showed that heart failure facilitates acute shortening of the APD immediately after VF termination [73].
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br Discussion There are many reports on the effectiveness
2019-04-26

Discussion There are many reports on the effectiveness of pacing therapy for hypertrophic obstructive cardiomyopathy. Fananapazir et al. reported that long-term right ventricular apical pacing improved both the left ventricular outflow tract gradient and subjective symptoms [3]. Maron et al. repo
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focal adhesion kinase PPCL were associated with a
2019-04-26

PPCL were associated with a very poor prognosis. The median survival duration according to published small trials was short, ranging from 7 to 13 months, with less than 10% of patients having a median survival of more than 5 years. In the largest recently published epidemiological study, the median
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br Approval statement br Role of the funding source
2019-04-26

Approval statement Role of the funding source Conflict of interest Acknowledgments Introduction Osteosarcoma (OS) is the most common malignancy of bone, mainly affecting children, adolescents and young adults. According to the American Cancer Society, 750–900 new cases of OS are diagn
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Cell adhesion to extracellular matrix requires the interacti
2019-04-26

Cell adhesion to extracellular matrix requires the interaction of different molecules like selectins, cadherins and integrins [21]. Especially αvβ3 integrin has been proposed to mediate the adhesion of malignant cells in different entities such as multiple myeloma and breast cancer [22,23]. Upon exp
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br Materials and methods A retrospective questionnaire surve
2019-04-26

Materials and methods A retrospective questionnaire survey was conducted among 299 JHRS institutions from December 2012 to January 2013. Patients with persistent AF who underwent TEE for elective ECV were included. LA thrombus incidence, risk factors for thrombus formation as indicated by the CHA
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