• br Primary biliary cholangitis Primary biliary

  2019-04-23

  

  Primary biliary cholangitis Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is another rare but devastating immune-mediated cholangiopathy. Similar to PSC, PBC is characterized by portal inflammation leading to fibrosis and eventually cirrhosis. Distinct from PSC

• Studies of strategies to reduce greenhouse gas emissions and

  2019-04-23

  

  Studies of strategies to reduce greenhouse gas emissions and improve health in urban environments have shown the potential to achieve both environmental and health improvements. For example, modelled effects of low emission vehicles and increased walking and cycling in London and Delhi showed major

• Previous studies have demonstrated localization of miR

  2019-04-23

  

  Previous studies have demonstrated localization of miR-21 staining in stromal pimaricin of OSCC associated with the tongue and mouth floor—this might be a useful prognostic predictor. We also observed miR-21 staining in the stromal cells of tumors. However, since multiple lines of evidence indicate

• In the current era nearly all cases of hormone receptor

  2019-04-22

  

  In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud

• El texto de Paz nos permite

  2019-04-22

  

  El texto de Paz nos permite contemplar el estado como una experiencia poética y una experiencia vital. Esto se debe en gran parte al énfasis que se pone en el cuerpo order BTS lo largo de , y más propiamente en el cuerpo que avanza en el sendero de Galta. La caminata física y la creación poética se

• Gender transformative policy and cultural

  2019-04-22

  

  Gender transformative policy and cultural reforms are also crucial to change prevailing norms and customs that devalue women and girls. Implementation and enforcement of non-discriminatory policies and practices that require gender equity in inheritance, property rights, education, and civil liberti

• br En relaci n con este ltimo tipo de

  2019-04-22

  

  En relación con este último tipo de poesía, la escéptica, Baldomero Sanín Cano publica el artículo emblemático de la crítica modernista “Núñez, poeta” en 1888 en La Sanción. En este sentido, el crítico colombiano, David Jiménez afirma que este artículo “contiene ya los planteamientos fundamentales

• Chronic myelogenous leukemia blast crisis is highly

  2019-04-22

  

  Chronic myelogenous leukemia blast crisis is highly refractory to standard induction chemotherapy, with a response rate of less than 20–30% [12,13]. In patient\'s with Imatinib resistant disease Dastanib and Nilotinib can help achieve hematological response however neither drug has been reported to

• Cancer stem cells are capable of differentiation and self re

  2019-04-22

  

  Cancer stem (-)-JQ1 are capable of differentiation and self-renewal. In 1994, CSCs were described for the first time. Hematological malignance is the best evidence to support the existence CSCs. TPC (tumor Propagating cell) is the other phrase that has been used for cancer stem cells. CSCs presents

• ibotenic acid br In their Comment on

  2019-04-20

  

  In their Comment on the use of antenatal corticosteroids to reduce preterm infant deaths, Kishwar Azad and Anthony Costello advise “extreme caution” before scale-up in low-income settings. They emphasise maternal sepsis as a concern but cite only one trial in which dexamethasone resulted in a sign

• In recent years the impact that food production and

  2019-04-20

  

  In recent years, the impact that food production and consumption have had on the environment has received increasing international attention. Some food production practices and consumption behaviours are putting the environment under a great stress, contributing to climate change. The food sector ac

• Roughly years have gone by

  2019-04-20

  

  Roughly 15 years have gone by since the identification of the main characters involved in the interplay of the RANK–RANKL system. This gave rise to the race for elucidating their biological role . In those years, in vivo silencing experiments for both Receptor Activator of Nuclear Factor κ B (RANK)

• Introduction Bone metastases are a common manifestation of c

  2019-04-20

  

  Introduction Bone metastases are a common manifestation of cancer [1]. Most patients present with pain and impaired mobility, while others can develop complications such as pathological fractures and mpges-1 inhibitors of the spinal cord or cauda equina [2]. Many randomized studies have been condu

• Certainly dynamic interactions between DTCs and stromal cell

  2019-04-20

  

  Certainly, dynamic interactions between DTCs and stromal gpr44 inhibitor within the bone microenvironment disrupt bone homeostasis, which is normally tightly controlled, to fuel metastatic progression [18] (Table 1). For example, it is well established that osteolytic breast cancer DTC-derived facto

• Por otro lado cabe subrayar que esta eleg a de

  2019-04-20

  

  Por otro lado, cabe subrayar que esta “elegía” de Pellicer se asemeja al género precolombino del icnocuicatl, los “Canto[s] de desolación, de orfandad” (Garibay 1992: 89). Según Garibay, estos cantos precolombinos “tienen parentesco con las elegías […] de los poetas de Occidente, en que se canta la

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