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Array and complete genomic hybridization based methods are n
2018-11-02

Array and complete genomic hybridization-based methods are now being used to detect deletions and amplifications that are considerably shorter than the resolution of cytogenetic techniques. Our data provides additional evidence of accrual of CNVs with extended culture, potentially as a result of rep
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dihydrochloride The goals of the current study were
2018-11-02

The goals of the current study were to investigate the changes in anal sphincter pressure after IV or IM injection of MSCs in our previously established animal models. Our models (Salcedo et al., 2010; Zutshi et al., 2009a) allow measurement of anal sphincter pressure and EMG in vivo in a repeated,
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Activin Nodal SMAD signaling is necessary
2018-11-02

Activin/Nodal-SMAD2/3 signaling is necessary and sufficient for human endoderm induction (Brown et al., 2011; D’Amour et al., 2005), but many other signaling pathways, particularly the WNT signaling pathway (Bone et al., 2011; Hay et al., 2008), also modulate DE differentiation (Mfopou et al., 2010)
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Why ectopic BRIGHT knockdown was
2018-11-02

Why ectopic BRIGHT knockdown was capable of stimulating reprogramming by the conventional 4F method but not singularly is unclear. While BRIGHT levels in MEFs are modest compared to hematopoietic tissues (Webb et al., 2011), we were only able to achieve ∼75% reduction in transcript levels (Figure S1
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The karyotype of the BIOT LOAD iPSC line
2018-11-02

The karyotype of the BIOT-4828-LOAD iPSC line was determined with Giemsa-banding, proving normal diploid 46, XX karyotype, without any detectable abnormalities (Fig. 1B). Expression of pluripotency markers was examined by immunocytochemistry staining, using vegf tyrosine kinase inhibitor against h
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br Experimental Procedures br Acknowledgments br Introductio
2018-11-02

Experimental Procedures Acknowledgments Introduction There are three distinct and differentially regulated stages in mammary gland development (embryonic, pubertal, and pregnancy/lactation), and the most substantial remodeling is postnatal (Gjorevski and Nelson, 2011). The mammary epitheliu
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br Results To develop iPSC
2018-11-02

Results To develop iPSC-based model systems of disease, we first prepared a bank of >60 iPSC clones (ten clones per donor; partial set and reprogramming methodology described previously [Mills et al., 2013; Somers et al., 2010]) derived from the dermal fibroblasts of three control individuals wit
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Genome wide screens have identified many
2018-11-02

Genome-wide screens have identified many potential regulators of stem cell function. These include genes with established roles in transcription regulation, cell growth, and differentiation, as well as genes whose function is largely unknown or remains to be validated in the context of stem cell bio
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The underlying idea of the tomographic method is in
2018-11-02

The underlying idea of the tomographic method is in reconstructing f(x, y), i.e. the density distribution function (or distribution of any other quantity) in the plane [3]. The initial data are sets of Radon images Rφ(s) that are projections of the functions f(x, y) on the set of the corresponding s
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Platelet rich plasma and other blood
2018-11-02

Platelet-rich plasma and other blood separation products have been used in human and veterinary medicine for over 20years. Numerous studies have proved the therapeutic effect of these products resulting from biological activity of the growth factors contained in platelets. Platelets are known to co
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Scale similarity criteria the Rayleigh number and the
2018-11-02

Scale similarity criteria (the Rayleigh number and the rotation parameter, constructed from the scale quantities) specified in the course of the simulations, were determined for the conjugate and the non-conjugate settings as follows: where ΔT0 is the temperature difference (ΔT0=–). In the conjuga
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br Acknowledgements This paper is designated
2018-11-02

Acknowledgements This paper is designated a Core Paper of the Child Community Health Network (CCHN) because it mitotic inhibitors reflects major ideas and work considered central to our network. Accordingly, the last designated author is the network itself, preceded by the names of those on the
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Thematic synthesis was used to identify important and recurr
2018-11-02

Thematic synthesis was used to identify important and recurrent themes (conducted in 2015) (Thomas & Harden, 2008). This method was developed based on the qualitative analytical technique ‘thematic analysis’ and borrows from traditional systematic review methods. It was developed with the aim that t
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CB-5083 To date there is no empirical
2018-11-02

To date, there is no empirical research published that investigates individuals’ mental health outcomes surrounding the 2005 London terror attacks, whilst considering the role of social capital. This study attempts to fill this CB-5083 lacuna. By employing panel data and following the same individua
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While the preponderance of evidence thus far has
2018-11-02

While the preponderance of evidence thus far has linked religiosity and health in a positive way, effects are not universally beneficial. Certain aspects and measures of religiosity have been shown to be disadvantages to health. For instance, religion has been found to induce anxiety when it adrener
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