• The role of circulating physiologic concentrations

  2024-03-02

  

  The role of circulating physiologic concentrations of FGF21 in glucose metabolism, however, remains unclear. Circulating FGF21 levels in obese and diabetic rodents, and in patients with type 2 diabetes are significantly higher than those in controls without diabetes [4], [5], [6]. On the other hand,

• In fact serotonin is a major modulator of dopaminergic DA

  2024-03-02

  

  In fact, serotonin is a major modulator of dopaminergic (DA) neuronal activity through the 5-HT2C receptor. Studies have shown that the selective 5-HT2C receptor agonist Ro60-0175 blocks the burst-firing of mesolimbic DA neurons, which project from the ventral tegmental area (VTA) to the nucleus acc

• We found that several anticancer

  2024-03-02

  

  We found that several anticancer drugs inhibit 5-HT3 KU14R current in vitro. Several studies have suggested that 5-HT3 receptor antagonists have anti-mitogenic and apoptotic effects on colorectal and breast cancer cell lines (Ataee et al., 2010, Hejazi et al., 2015). Irinotecan is used frequently t

• The initial observations indicating a crucial role for elect

  2024-03-02

  

  The initial observations indicating a crucial role for teva 3026 australia transfer in 17,20 lyase activity were that the molar ratio of POR to P450c17 is three- to four-fold higher in porcine testes than in porcine adrenals, and that adding purified POR to porcine P450c17 in vitro increased 17,20

• br Results br Discussion The

  2024-03-02

  

  Results Discussion The A. nidulans Aurora kinase displays diverse locations during mitosis and we show here that it also locates to hyphal regions where septa subsequently form, to the septal pore region of newly formed septa and displays a DMAP specific location to mature septa. To investiga

• V ATPase is a complex enzyme that is composed

  2024-03-02

  

  V-ATPase is a complex enzyme that is composed of several subunits, which are assembled into two domains: trans-membrane (V0) and cytosolic (V1) domains [3,5]. Epididymal epithelial Kobe0065 of rats has been reported to contain V-ATPase which is distributed at the apical pole of the narrow and clear

• br Experimental Procedures br Acknowledgments This work was

  2024-03-02

  

  Experimental Procedures Acknowledgments This work was supported by NIH/National Human Genome Research Institute (NHGRI)R00 HG006922 and NIH/NHGRIR01 HG008974 (to J.G.), the Huntsman Cancer Institute, and the Women’s Cancers Disease-Oriented Team at the Huntsman Cancer Institute. Research repor

• Plant pathogenic fungi have caused a lot of

  2024-03-01

  

  Plant pathogenic fungi have caused a lot of economic losses to agricultural production worldwide every year. It is necessary to develop an bio-sourced antifungal agent for agricultural use. Many researches have shown that the antifungal activity of quaternized chitosan derivatives is mainly affected

• br Acknowledgments br Introduction Angiotensin II

  2024-03-01

  

  Acknowledgments Introduction Angiotensin II (AngII) is among the most potent vasoactive substances produced in humans. Its effects are numerous, from vasoconstriction to control of fluid and electrolytes balances. Many of the physiological and pathological effects of AngII are mediated by the

• br AR mediated actions in cells

  2024-03-01

  

  AR-mediated actions in simvastatin zocor of the vascular wall Sex hormones may influence the size and composition of atherosclerotic lesions indirectly by modifying systemic cardiovascular risk factors such as plasma lipids profiles and insulin sensitivity; this aspect of their action is discuss

• In our sequential model for tau and A

  2024-03-01

  

  In our sequential model for tau and Aβ deposition, we included the tau deposition in the medial temporal Viroptic in the absence of Aβ deposition, which is a pathological definition of primary age-related tauopathy (PART). Although the tau pathologies in PART and AD are almost identical in their ne

• br Results br Discussion Cardiac dysfunction common complica

  2024-03-01

  

  Results Discussion Cardiac dysfunction, common complication of severe sepsis, is one cause of death in intensive care units. Accumulated evidence revealed the regulatory effect of autophagy on sepsis-induced cardiac dysfunction [15], [22], although the mechanisms in young and aging are not elu

• br Introduction Alzheimer s disease AD

  2024-03-01

  

  Introduction Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia. It is characterized by progressive and irreversible damage to different Bax channel blocker areas, resulting in cognitive impairment and behavioral changes (O'Neill, 2013, De Strooper and Kar

• WM-8014 In our previous study we found that the

  2024-03-01

  

  In our previous study we found that the total activity of aldehyde dehydrogenase in cancer WM-8014 of RCC is at the same level as in normal renal tissue [10]. These findings are similar to our results in serum patients with renal cancer. There is no significant difference between ALDH activity in s

• Human testicular peritubular cells HTPCs

  2024-03-01

  

  Human testicular peritubular cyclic adenosine monophosphate (HTPCs) are also the only human testicular cell type that can be isolated, cultured and studied in vitro (Albrecht et al., 2006, Mayerhofer, 2013). Results from recent studies indicate that their roles go beyond sperm transport and include

16350 records 193/1090 page Previous Next First page 上5页 191192193194195 下5页 Last page