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JP 1302 dihydrochloride receptor br Conflict of interest sta
2023-08-14

Conflict of interest statement Benign prostatic hyperplasia (BPH) is a highly complex process characterized by an increased number of epithelial and stromal JP 1302 dihydrochloride receptor in the transition zone. , , Autopsy studies by McNeal detail the evolution of histological changes with
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Aurora A overexpression is also related to the activation of
2023-08-12

Aurora-A overexpression is also related to the activation of NF-κB, a potent anti-apoptotic effector that may play a role in preventing apoptosis in cancer resveratrol [18]. These data show that we are still at the beginning of unraveling the complex mechanism by which these gene products and prot
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Secondly leptin has been shown
2023-08-12

Secondly, leptin has been shown to enhance aromatase mRNA expression, aromatase content and its enzymatic activity in epithelial breast cancer Vicriviroc maleate by inducing promoters II and I.3 via an enhanced binding of transcription activator protein 1 (AP-1) complex to specific DNA sites in the
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Kuda et al reported that the activity of
2023-08-12

Kuda et al. (1997) reported that the activity of aminopeptidase A (ApA) but not aminopeptidase B (ApB) nor aminopeptidase N (ApN) was decreased in plasma from patients with Alzheimer's disease (AD). More recently Puertas et al. (2013) reported that the activities of plasma ApA, ApB, ApN and IRAP wer
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The overall adjustment the non toxicity and the addiction fr
2023-08-12

The overall adjustment, the non-toxicity and the addiction-free treatment methods are the advantages of EA. EA treatment for depression has achieved great clinical effect in recent years (Dong et al., 2017). The clinical practice guideline of the American college of physicians (ACP) have pointed out
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br Conflict of interest br Financial support br Acknowledgme
2023-08-12

Conflict of interest Financial support Acknowledgments This work was supported by the Japanese Millennium project. We thank all members of the Center for Genomic Medicine of RIKEN and Dainippon-Sumitomo Pharma Co., Ltd. for supporting this study. We are also grateful to members of the Hiros
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Azaserine br ACK signaling partners ACK interacts
2023-08-12

ACK1 signaling partners ACK1 interacts with and tyrosine phosphorylates many cellular proteins regulating critical cellular processes [11]. While ACK1 shares common intracellular effectors such as AKT with other signaling pathways, it imparts specificity to signaling by phosphorylating effectors
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br Funding The present study was
2023-08-11

Funding The present study was funded by The Scientific and Technological Research Council of Turkey (TUBITAK) within Research Program 1001, unique project number: 214S349. Introduction The apelin receptor, also called APJ or angiotensin receptor-like 1 was first cloned in 1993 due to its stro
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To our knowledge this study
2023-08-11

To our knowledge, this study collected all published research of occurrence of Ryuvidine in water, sediment and aquatic organisms of typical Lakes by 2017 according to http://www.cnki.net/, https://xue.glgoo.net/, http://xueshu.baidu.com/, and http://www.sciencedirect.com/. Some information of Lake
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Natural compounds present in medicinal and
2023-08-11

Natural compounds, present in medicinal and/or nutritional plants as well as in macrofungi sources, have stimulated a great interest from the pharmaceutical industry. Different natural compounds such as phenolic compounds, alkaloids, terpenoids among others, have shown strong antiangiogenic effects
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Accumulating evidence indicates that experience dependent al
2023-08-11

Accumulating evidence indicates that experience-dependent alterations in glutamate transmission in the NAc, such as those produced by repeated exposure to cocaine, involve alterations in postsynaptic signaling mediated by AMPA-type receptors (Pierce and Wolf, 2013, Wolf and Ferrario, 2010). In the N
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Whether similar mechanisms play a role in adiponectin signal
2023-08-11

Whether similar mechanisms play a role in adiponectin signal transduction and whether additional proteins are recruited to adiponectin receptors via APPL1 has not been analysed so far. Although it has been clearly established that APPL1 is a downstream adaptor protein in adiponectin signal transduct
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br Acknowledgments br Introduction Within the classical secr
2023-08-11

Acknowledgments Introduction Within the classical secretory pathway, transmembrane and soluble cargos travel via the endoplasmic reticulum (ER) and Golgi apparatus en route to their final destinations [1]. However, at a post-Golgi level, trafficking routes can diverge. In this context, the tra
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GSK2879552 The present study showed for the
2023-08-11

The present study showed, for the first time, that hirsutine, hirsuteine, rhynchophylline, isorhynchophylline, corynoxeine, and isocorynoxeine in yokukansan can inhibit the 5-HT3 receptor current. These data indicate that part of the effect of yokukansan against the behavioral and psychological symp
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hydroxydopamine OHDA is a selective
2023-08-11

6-hydroxydopamine (6-OHDA) is a selective catecholaminergic neurotoxin mainly used to generate lesions in the nigrostriatal pathway in rats (Ungerstedt, 1968). The most common use of 6-OHDA is via unilateral injection into the rat medial forebrain bundle (MFB). DA depletion, nigral DA cell loss, and
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